samfurori
Babban ingancin L-Glutathione Rage CAS 70-18-8 don Glutathione Kula da Fata
Bayanin samfur
Saukewa: C10H17N3O6S
MW: 307.32
Saukewa: 70-18-8
1.Glutathione wani fili ne na tripeptide wanda aka tattara ta glutamic acid, cysteine da glycine ta hanyar haɗin peptide.Shi ne mafi mahimmanci ƙananan mercaptan na kwayoyin halitta a cikin ƙwayoyin mammalian ƙarƙashin damuwa na antioxidant.
2.Glutathione (GSH) wani fili ne na tripeptide wanda aka kafa ta hanyar condensation na glutamic acid, cysteine da glycine ta hanyar haɗin peptide.Sunan sinadarai γ- Tsarin tsarin l-glutamyl-l-cysteyl-glycine an nuna shi a cikin littafi na 1chemical.Bisa ga tsarin tsari a cikin adadi, GSH ya bambanta da sauran peptides da sunadarai.Akwai nau'in peptide na musamman a cikin kwayoyinsa, wanda aka yi da glutamic acid γ-Carboxyl (- COOH) da cysteine α- Peptide bond wanda aka samu ta hanyar natsuwa na amino – (- NH2).
3.The kwayoyin nauyi na glutathione ne 307.33, da narkewa batu ne 189 ~ 193 ℃ (bazuwar), da crystal ne colorless, m, siriri shafi, da kuma isoelectric batu ne 5.93.Yana narkewa cikin ruwa, dilute barasa, ruwa ammonia da methyl formamide, amma insoluble a barasa, ether da acetone.GSH kawai yana da aikin physiological a cikin kwayoyin halitta, kuma GSSG na iya taka muhimmiyar aikin ilimin lissafi bayan raguwa.GSH ba shi da sauƙi don adanawa a ƙarƙashin babban aikin ruwa, kuma ana iya adana shi na dogon lokaci kawai lokacin da ake sarrafa aikin ruwa a ƙasa da 0.3.Nazarin ya nuna cewa a cikin bitamin ccchemicalbook aqueous bayani mai dauke da GSH (ph3.3), saboda karfi da raguwa na bitamin C, GSH a cikin maganin ba zai zama oxidized zuwa GSSG ba, amma saurin rushewar sa yana da sauri;GSSG a cikin bitamin C maganin ruwa ba zai canza zuwa GSH ba, kuma kwanciyar hankalin ajiyarsa yana da kyau sosai.Bugu da ƙari, GSSG da aka ci da baki za a iya rage zuwa GSH a cikin babba na ƙananan hanji, da kuma saman ƙananan ƙwayoyin epithelial na hanji γ- GTP (wanda ke lalata GSH zuwa glutamic acid da Cys Gly) kuma dipeptidase kuma yana iya taka muhimmiyar rawa. ayyuka.
4.Glutathione yana da yawa a cikin dabbobi da tsire-tsire, kuma abubuwan da ke cikin yisti mai yin burodi, ƙwayar alkama da hanta dabba yana da girma sosai, har zuwa 100 ~ 1000mg/100g;Hakanan yana da wadatar jinin mutum da na dabba, kamar 26chemicalbook ~ 34mg/100g a jinin mutum, 58 ~ 73mg/100g a jinin kaji, 10 ~ 15mg/100g na jinin alade da 14 ~ 22mg/100g a jinin kare.Hakanan ana samun GSH a yawancin kayan lambu, dankali da hatsi.
Aikace-aikace
1.Reduced glutathione wani karamin kwayoyin peptide ne, wanda ke samuwa da yawa a cikin kwayoyin halitta, musamman a cikin kwayoyin hanta.Yana iya kare membrane na hanta, inganta aikin enzyme hanta, da haɗuwa da yawancin sinadarai masu guba a cikin littafin sinadarai don lalata.Yana da tasiri mai kyau akan raunin hanta, hanta cirrhosis da sauran cututtuka da suka haifar da guba na miyagun ƙwayoyi, barasa da sauran dalilai.
2.It yana da ayyuka na antioxidation, scavenging free radicals, detoxification, inganta rigakafi, jinkirta tsufa, anti-ciwon daji, anti radiation lalacewa da sauransu.
3.Biochemical reagents da antidotes aka yafi amfani da guba na nauyi karafa, acrylonitrile, fluoride, carbon monoxide da Organic kaushi.
4.Endogenous antioxidants cewa taka muhimmiyar rawa a rage reactive oxygen jinsunan kafa a lokacin cell metabolism da kwatsam numfashi.Glutathione-S-transferase yana haifar da samuwar glutathione sulfide tare da xenobiotics, leukotrienes da sauran kwayoyin halitta tare da cibiyoyin electrophilic.Glutathione kuma yana samar da haɗin gwiwar disulfide tare da ragowar cysteine a cikin sunadaran.Ta hanyar waɗannan hanyoyin, yana iya samun wani bakon sakamako na rage tasirin maganin ciwon daji.
